The Tikvesh Wine Route Foundation is a non-profit organization established in 2006 by four municipalities in the Tikvesh region and by two private entrepreneurs from the sector of tourism and wine. The Foundation has support and representation on the Board from three ministries: economy, agriculture and culture, as well as representatives from the wine and tourism sector and member of the faculty of tourism in Ohrid. It is well and widely known as the first and only tourism, wine and food cluster in FYR of Macedonia. The foundation is a member of Iter Vitis – wine routes of Western Europe as well as WCTE network of South East Europe.
The Tikvesh Wine Route foundation is working on the development of alternative tourism in the region, with special emphasis in wine tourism. It has accomplished several bigger and many smaller projects in the past. A few of them: Wine museum in Negotino, Tourist info centre, training for 100 people for tourism and hospitality, development of promotional materials, organization of study trips, visit of groups of journalists from the country and abroad, forums, conferences, tourist events, surveys, signs for the wine routes, applications to transnational and cross border cooperation programs and many more.