The European Strategy Forum on Research Infrastructures (ESFRI) identifies in this report 35 large-scale infrastructure projects to cover needs of the research community in the next 10 years. In seven thematic fields, projects with estimated costs of some 14 billion EUR are identified.

1. Social Sciences and Humanities: CESSDA (facility to provide and facilitate access of researchers to high quality data for social sciences), CLARIN (research infrastructure to make language resources and technology available and useful to scholars of all disciplines), DARIAH (digital infrastructure to study the sources of cultural heritage institutions), EROHS (central and distributed facility to promote and ensure cooperation and integration of data, technologies and policies), ESS (European Social Survey), SHARE (data infrastructure for empiric economic ans social science analysis of the on-going changes due to population ageing)
2. Environmental Sciences: AURORA BOREALIS (European Polar Research Icebreaker), EMSO (Multidisciplinary Seafloor Observatory), EUFAR (Long Range Tropospheric Aircraft), EURO ARGO (Ocean Observing buoy system), IAGOS-ERI (Climate Change Observation from 20 commercial aircrafts), ICOS (Integrated Carbon Observation System), LIFE WATCH (Infrastructure for research on the protection, management and sustainable use of biodiversity)
3. Energy: HIPER (High Power long pulse Laser for “fast-ignition” Fusion), IFMIF (International Fusion Materials Irradiation Facility), JHR (High flux reactor for Fission Reactors Materials Testing)
4. Biomedical and Life Sciences: EATRIS (Network of new research centres to translate basic discoveries into clinical interventions in major diseases), European Bio-banking and Biomolecular Resources (Network of existing and new biobanks and molecular resources), INFRAFRONTIER (Distributed infrastructure for the archiving and phenotyping of mice as models for studying human diseases), Infrastructure for Clinical Trials and Biotherapy Facilities (Network of clinical research centres, clinical trials and biotherapy facilities for therapeutic innovations), Integrated Structural Biology Infrastructure (Network of centres for integrated structural biology), Upgrade of European Bio-Informatics Infrastructure (Shared platform for data resources in the Life Sciences based on a major upgrade of EBI)
5. Materials Sciences: ELI (Extreme Light intensity short pulse Laser), ESRF Upgrade (Upgrade of the European Synchrotron Radiation Facility), ESS (European Spallation Source for neutron spectroscopy), European XFEL (Hard X-ray Free Electron Laser in Hamburg), ILL 20/20 (Upgrade of European Neutron Spectroscopy Facility), IRUVX-FEL (Infrared to soft X-rays complementary Free Electron Lasers), PRINS (Paneuropean Infrastructure for Nanostructures and Nanoelectronics)
6. Astronomy, Astrophysics, Nuclear and Particle Physics: ELT (European Extremely Large optical telescope), FAIR (Facility for Antiproton and Ion Research), KM3NET (Underwater Neutrino Observatory), SKA (Square Kilometer Radiotelescope Array), SPIRAL2 (Production and study of rare isotope Radioactive beams) *proposals related to particle physics and space science are presented by CERN and ESA
7. Computation and Data Treatment: EU-HPC (Integrated European High Power Computing Service)

The document describes the landscape of the different fields as well as the individual projects.