First open source model of the spike protein COVID-19 uses to enter human cells

Researchers at Cambridge University working with counterparts from Seoul National University in South Korea and Lehigh University in the US, have produced the first open-source atom-by-atom animated model of the spike protein by which the COVID-19 virus locks onto and enters human cells.

Its central role in viral entry makes the spike protein a main target for vaccine and antiviral drug development, and the model makes it possible to simulate molecular dynamics in silico. Researchers will be able to visualise molecular level interactions that cannot be observed in any other way. The details are in a paper published online in The Journal of Physical Chemistry B.

See the "just accepted" paper in the attachment. “Just Accepted” manuscripts have been peer-reviewed and accepted for publication. They are postedonline prior to technical editing, formatting for publication and author proofing.

Original source: https://sciencebusiness.net/covid-19/news/live-blog-rd-response-covid-19-pandemic, https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.0c04553

Geographical focus
  • Europe
  • European Union (EU 28)
  • International; Other
Scientifc field / Thematic focus
  • Cross-thematic/Interdisciplinary
Attachments

Entry created by Admin WBC-RTI.info on June 25, 2020
Modified on June 25, 2020